Epigenetic control of early embryonic development in Zebrafish

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We are interested in understanding the regulation of cell fate specification and cellular movements during early embryogenesis, especially focused on gastrulation. As the developmental biologist Lewis Wolpert rightly said, "It is not birth, marriage, or death, but gastrulation which is truly the most important time in your life". Our lab focuses on delineating the function of vertebrate lineage-specific chromatin organizers during this important stage of development. This is accomplished by employing genetics, imaging and genome-wide studies to identify novel chromatin organizers and functionally characterize them.