Laboratory of Chromatin Biology & Epigenetics

Most Recent

Ramanujam, P. L., Mehrotra, S., Kumar, R. P., Verma, S., Deshpande, G., Mishra, R. K., & Galande, S. (2021). Global chromatin organizer SATB1 acts as a context-dependent regulator of the Wnt/Wg target genes. Scientific reports, 11(1), 3385.

Naik, S., Unni, M., Sinha, D., Rajput, S. S., Reddy, P. C., Kartvelishvily, E., Solomonov, I., Sagi, I., Chatterji, A., Patil, S., & Galande, S. 2020. Differential tissue stiffness of body column facilitates locomotion of Hydra on solid substrates. The Journal of Experimental Biology, jeb.232702. Advance online publication.

Reddy, P. C., Gungi, A., Ubhe, S., & Galande, S. 2020. Epigenomic landscape of enhancer elements during Hydra head organizer formation. Epigenetics & Chromatin, 13(1), 43

Patta, I., Madhok, A., Khare, S., Gottimukkala, K.P., Verma, A., Giri, S., Dandewad, V., Seshadri, V., Lal, G., Misra-Sen, J. and Galande, S., 2020. Dynamic regulation of chromatin organizer SATB1 via TCR-induced alternative promoter switch during T-cell development. Nucleic Acids Research.

Complete list of publications

Publications in past 7 years

2021

Ramanujam, P. L., Mehrotra, S., Kumar, R. P., Verma, S., Deshpande, G., Mishra, R. K., & Galande, S. (2021). Global chromatin organizer SATB1 acts as a context-dependent regulator of the Wnt/Wg target genes. Scientific reports, 11(1), 3385.

2020

Reddy, P. C., Gungi, A., Ubhe, S., & Galande, S. 2020. Epigenomic landscape of enhancer elements during Hydra head organizer formation. Epigenetics & Chromatin, 13(1), 43

Naik, S., Unni, M., Sinha, D., Rajput, S. S., Reddy, P. C., Kartvelishvily, E., Solomonov, I., Sagi, I., Chatterji, A., Patil, S., & Galande, S. 2020. Differential tissue stiffness of body column facilitates locomotion of Hydra on solid substrates. The Journal of Experimental Biology, jeb.232702. Advance online publication.

Mehrotra, S., Bansal, P., Oli, N. and Galande, S., 2020. Defective Proventriculus regulates cell specification in the gastric region of Drosophila intestine. Frontiers in Physiology, 11, p.711.

Patta I, Madhok A, Khare SP, Gottimukkala KP, Verma A, Giri S, Dandewad V, Seshadri V, Lal G, Misra-Sen J and Galande S. 2020. Dynamic regulation of chromatin organizer SATB1 via TCR induced alternative promoter switch during T-cell development. Nucleic Acids Res (May 11:gkaa321. doi: 10.1093/nar/gkaa321. Online ahead of print). PMID: 32392347.

Lloyd KCK, Adams DJ, Baynam G, Beaudet AL, Bosch F, Boycott KM, Braun RE, Caulfield M, Cohn R, Dickinson ME, Dobbie MS, Flenniken AM, Flicek P, Galande S, Gao X, Grobler A, Heaney JD, Herault Y, de Angelis MH, Lupski JR, Lyonnet S, Mallon AM, Mammano F, MacRae CA, McInnes R, McKerlie C, Meehan TF, Murray SA, Nutter LMJ, Obata Y, Parkinson H, Pepper MS, Sedlacek R, Seong JK, Shiroishi T, Smedley D, Tocchini-Valentini G, Valle D, Wang CL, Wells S, White J, Wurst W, Xu Y, Brown SDM. 2020. The Deep Genome Project. Genome Biol. 21:18. doi: 10.1186/s13059-020-1931-9.

Reddy PC, Pradhan SJ, Karmodiya K, Galande S. 2020. Origin of RNA Polymerase II pause in eumetazoans: Insights from Hydra. J Biosci. 45. pii: 8.

2019

Narlikar G, Galande S. 2019 Topical collection on Chromatin Biology and Epigenetics. J Biosci. 45. pii: 1.

Reddy, P.C., Gungi, A., Ubhe, S., Pradhan, S.J., Kolte, A. and Galande, S., 2019. Molecular signature of an ancient organizer regulated by Wnt/β-catenin signalling during primary body axis patterning in Hydra. Communications Biology, 2(1), pp.1-11.

Khare, S.P., Shetty, A., Biradar, R., Patta, I., Chen, Z.J., Sathe, A.V., Reddy, P.C., Lahesmaa, R. and Galande, S., 2019. NF-κB Signaling and IL-4 Signaling Regulate SATB1 Expression via Alternative Promoter Usage During Th2 Differentiation. Frontiers in Immunology, 10.

Muley, V.Y., Akhter, Y. and Galande, S., 2019. PDZ Domains Across the Microbial World: Molecular Link to the Proteases, Stress Response, and Protein Synthesis. Genome Biology and Evolution, 11(3), pp.644-659.

Tripathi, S. K., Välikangas, T., Shetty, A., Khan, M. M., Moulder, R., Bhosale, S. D., Komsi, E., Salo, V., De Albuquerque, R. S., Rasool, O., Galande, S., Elo, L. L., & Lahesmaa, R. (2019). Quantitative Proteomics Reveals the Dynamic Protein Landscape during Initiation of Human Th17 Cell Polarization. iScience, 11, 334–355.

Balyan, R., Gund, R., Chawla, A.S., Khare, S.P., Pradhan, S.J., Rane, S., Galande, S., Durdik, J.M., George, A., Bal, V. and Rath, S., 2019. Correlation of cell‐surface CD 8 levels with function, phenotype and transcriptome of naive CD 8 T cells. Immunology, 156(4), pp.384-401.

2018

Naik, Rutika, and Sanjeev Galande. "SATB family chromatin organizers as master regulators of tumor progression." Oncogene (2018): 1.

Mir R, Sharma A, Pradhan SJ, Galande S. (2018). Regulation of Transcription Factor SP1 by the β-Catenin Destruction Complex Modulates Wnt Response. Molecular and Cellular Biology Oct 2018, 38 (22) e00188-18

Jangid RK, Kelkar A, Muley VY, Galande S. (2018). Bidirectional promoters exhibit characteristic chromatin modification signature associated with transcription elongation in both sense and antisense directions. BMC Genomics. 2018 May 2;19(1):313. doi: 0.1186/s12864-018-4697-7.

Manjunath GP, Ramanujam PL, Galande S. (2018).Structure-function relations in PDZ-domain containing-proteins: Implications for protein networks in cellular signalling. J Biosci. 2018 Mar;43(1):155-171.

2017

Sawant AA, Galande S, Srivatsan SG (2017). Imaging Newly Transcribed RNA in Cells by Using a Clickable Azide-Modified UTP Analog. Methods Mol Biol. 2018;1649:359-371.

Muralidharan B, Keruzore M, Pradhan SJ, Roy B, Shetty AS, Kinare V, D'Souza L, Maheshwari U, Karmodiya K, Suresh A, Galande S, Bellefroid EJ, Tole S. (2017). Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control the Neuron-Glia Cell-Fate Switch in the Developing Hippocampus. J Neurosci. 2017 Nov 15;37(46):11245-11254.

Reddy PC, Ubhe S, Sirwani N, Lohokare R, Galande S. (2017). Rapid divergence of histones in Hydrozoa (Cnidaria) and evolution of a novel histone involved in DNA damage response in hydra. Zoology (Jena). pii: S0944-2006(16)30135-0.

Muralidharan B, Khatri Z, Maheshwari U, Gupta R, Roy B, Pradhan SJ, Karmodiya K, Padmanabhan H, Shetty AS, Balaji C, Kolthur-Seetharam U, Macklis JD, Galande S, Tole S. (2017). LHX2 Interacts with the NuRD Complex and Regulates Cortical Neuron Subtype Determinants Fezf2 and Sox11. J Neurosci. 2017 Jan 4;37(1):194-203.

Sako, K., Pradhan, Saurabh J., Barone, V., Inglés-Prieto, Á., Müller, P., Ruprecht, V., Čapek, D., Galande, S., Janovjak, H., and Heisenberg, C.-P., 2016. Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation. Cell Reports.

2016

Gottimukkala, K.P., Jangid, R., Patta, I., Sharma, A., Misra-Sen, J. and Galande, S., 2016. Regulation of SATB1 during thymocyte development by TCR signaling. Molecular Immunology, 77, pp.34-43.

Sako, K., Pradhan, Saurabh J., Barone, V., Inglés-Prieto, Á., Müller, P., Ruprecht, V., Čapek, D., Galande, S., Janovjak, H., and Heisenberg, C.-P. Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation. Cell Reports.

Pusalkar, M., Ghosh, S., Jaggar, M., Husain, B.F.A., Galande, S., and Vaidya, V.A. (2016). Acute and Chronic Electroconvulsive Seizures (ECS) Differentially Regulate the Expression of Epigenetic Machinery in the Adult Rat Hippocampus. International Journal of Neuropsychopharmacology.

Sawant, A.A., Mukherjee, P.P., Jangid, R.K., Galande, S., and Srivatsan, S.G. (2016). A clickable UTP analog for the posttranscriptional chemical labeling and imaging of RNA. Organic & Biomolecular Chemistry 14, 5832-5842.

Sawant, A.A., Tanpure, A.A., Mukherjee, P.P., Athavale, S., Kelkar, A., Galande, S. and Srivatsan, S.G., 2016. A versatile toolbox for posttranscriptional chemical labeling and imaging of RNA. Nucleic Acids Research, 44(2), pp.e16-e16.

2015

Hardikar, A. A., Satoor, S. N., Karandikar, M. S., Joglekar, M. V., Puranik, A. S., Wong, W., Kumar, S., Limaye, A., Bhat, D. S., Januszewski, A. S., Umrani, M. R., Ranjan, A. K., Apte, K., Yajnik, P., Bhonde, R. R., Galande, S., Keech, A. C., Jenkins, A. J., & Yajnik, C. S. (2015). Multigenerational Undernutrition Increases Susceptibility to Obesity and Diabetes that Is Not Reversed after Dietary Recuperation. Cell metabolism, 22(2), 312–319.

Karmodiya, K., Pradhan, S.J., Joshi, B., Jangid, R., Reddy, P.C., and Galande, S. (2015). A comprehensive epigenome map of Plasmodium falciparum reveals unique mechanisms of transcriptional regulation and identifies H3K36me2 as a global mark of gene suppression. Epigenetics & Chromatin 8, 1-18.

Reddy, P.C., Sinha, I., Kelkar, A., Habib, F., Pradhan, S.J., Sukumar, R., and Galande, S. (2015a). Comparative sequence analyses of genome and transcriptome reveal novel transcripts and variants in the Asian elephant Elephas maximus. Journal of Biosciences 40, 891-907.

Reddy, P.C., Unni, M.K., Gungi, A., Agarwal, P., and Galande, S. (2015b). Evolution of Hox-like genes in Cnidaria: Study of Hydra Hox repertoire reveals tailor-made Hox-code for Cnidarians. Mechanisms of Development 138, Part 2, 87-96.

Pusalkar M, Suri D, Kelkar A, Bhattacharya A, Galande S, and Vaidya VA. (2015) Early stress evokes dysregulation of histone modifiers in the medial prefrontal cortex across the life span. Dev. Psychobiol. 58:198-210.

Mir R, Pradhan SJ, Patil P, Mulherkar R and Galande, S. (2015) Wnt/β-catenin signaling regulated SATB1 promotes colorectal cancer tumorigenesis and progression. Oncogene. 35:1679-1691.